Canines:
Positive results have been shown for skin and respiratory, digestive and genitourinary tract infections, and prostatitis, as well as for external otitis and injury infections. In prostatic tissues and fluids, it reaches concentrations higher than the MIC of almost all microorganisms that cause urinary tract infections.
Felines:
Clinical findings suggest that enrofloxacin is effective for the treatment of infections caused by opportunistic mycobacteria such as Mycobacterium fortuitum and M. smegmatis in cats. In vitro susceptibility data indicates that it should be effective against Bartonella spp. However, in vivo studies demonstrate that a treatment of several weeks is necessary, and that bacteremia does not disappear in all animals.